Dr Luca Marciani - Nottingham BRC

Dr Luca Marciani graduated in Physics at the University of Genoa in Italy. He worked in Milan and London before joining the University of Nottingham where he was awarded his PhD in Physics at the Sir Peter Mansfield Imaging Centre.

His personal expertise is in imaging the human gastrointestinal (GI) tract using magnetic resonance imaging (MRI). His research focuses on gastrointestinal physiology and pathology using MRI methods in combination with other physiological and behavioural techniques. Luca has a particular interest in in-body imaging of foods, beverages, dosage forms and formulations, intestinal fluid distribution and the development of novel MRI tests for GI motility and transit. He works within a team that has developed a unique cross-disciplinary collaboration between gastroenterologists, surgeons, physiologists, MRI physicists, pharmaceutical scientists, food scientists and industrial collaborators from the food and pharmaceutical industry in the UK and abroad. Luca has published 84 research papers and 11 book chapters, and is the first author on two patents.

Currently, Luca leads a NIHR Invention for Innovation (i4i) project developing, together with children and parents, a new MRI medical device to measure gastrointestinal transit in paediatric constipation. He also leads the UK part of a FDA-funded project with the University of Michigan, using MRI to study in vivo the fluid and motility environment of the undisturbed human gut, with a view to improve physiological relevance of in vitro testing methods and in silico transport analyses for prediction of bioperformance of oral dosage forms.

For further details: Dr Luca Marciani